The sepium lot represents all illicit substances found throughout the world of Bicolline. It is derived from a fantastical, multipurpose plant whose flowers, leaves, sap, and tubers can be prepared to produce a wide variety of stimulants, sedatives, and hallucinogens.

It is known for its military use, allowing fighters to battle in a frenzy while ignoring fear and pain. Some also attribute occult or entheogenic properties to it.